It promotes integrin (alphav beta3)-mediated cell binding Homo sapiens. Synonyms: KSPG osteomodulin, Keratan sulfate proteoglycan osteomodulin, OSAD, Osteoadherin, Osteomodulin, Buchaille, R. et al., Dage, J.L. The small leucine-rich repeat proteins, fibromodulin and osteoadherin, have N- terminal extensions with a variable number of O-sulfated tyrosine residues. KSPG osteomodulin antibody; OSAD antibody. Osteoadherin antibody; Osteoadherin proteoglycan antibody; Osteomodulin antibody; SLRR2C antibody. Jan 1, 2019 Osteoadherin (also termed osteomodulin) is encoded by the Omd gene and is a keratan sulfate proteoglycan of the class II subfamily of SLRPs. Mar 30, 2020 localization indicating that this reactivity was due to another KS-proteoglycan, possibly osteoadherin. (osteomodulin) which has known roles in Human Osteoadherin/Osteomodulin quantitates human Osteoadherin/ Osteomodulin in serum, plasma, supernatant.
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It had an apparent molecular mass of 85 kD under reducing conditions by SDS-PAGE. ELISA detected osteoadherin in bovine bone only, and immunohistochemical analysis of bovine fetal rib growth plate showed osteoadherin exclusively in primary bone spongiosa. Product Name: Human Osteoadherin ELISA Kit PicoKine™ See more Osteoadherin/OSAD/OMD products: Catalog# EK2017: Storage & Handling: Store at 4˚C for 6 months, at -20˚C for 12 months. The Human Osteoadherin IQELISA™ kit is an ultrasensitive ELISA utilizing qPCR detection for 10X more sensitivity with 10X less sample. Osteoadherin is highly expressed in mineralized tissues, including bone and dentin; however, it's precise roles remain unknown.
Although few previous reports show regulation of Omd expression by growth factors and signaling molecules, Rehn et al ( 30 ) reported that transforming growth factor-β (TGF-β) down-regulates Omd 1999-12-30 The Human Osteoadherin IQELISA™ kit is an ultrasensitive ELISA utilizing qPCR detection for 10X more sensitivity with 10X less sample. See more Osteoadherin/OSAD/OMD products: Catalog# EK2017: Storage & Handling: Store at 4˚C for 6 months, at -20˚C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.) Description: Sandwich High Sensitivity ELISA kit for Quantitative Detection of human Osteoadherin.
This modification combined with a number of aspartic and glutamic acid residues results in a highly negatively charged domain of less than 30 amino acids. We hypothesized that this domain shares functional properties with heparin 2000-02-01 Copying, scanning & printing Study spaces & reading rooms Sweden stands up for open access – cancels agreement with Elsevier LUBcat LIBRIS Osteoadherin is a recently described bone proteoglycan containing keratan sulfate. It promotes integrin (alphav beta3)-mediated cell binding (Wendel, M., Sommarin, Y., and Heinegârd, D. (1998) J. Cell Biol. 141, 839-847).
It promotes integrin (a vb 3)-mediated cell binding (Wendel, M., Sommarin, Y., and Heinegård, D. (1998) J. Cell Biol.
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Our Osteoadherin/OSAD/OMD Antibodies can be used in a variety of model species: Human, Mouse. Use the list below to choose the Osteoadherin/OSAD/OMD Antibody which is most appropriate for your research; you can click on each one to view full technical details, images, references, reviews and related products.
Other proteins exclusively restricted to bone include osteocalcin and BSP.
The small leucine-rich repeat proteins (SLRPs), fibromodulin and osteoadherin, have N-terminal extensions with a variable number of O-sulfated tyrosine residues.
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Author: Rehn, Anders. Date: 2008-06-04. A small cell-binding proteoglycan for which we propose the name osteoadherin was extracted from bovine bone with guanidine hydrochloride–containing EDTA. It was purified to homogeneity using a combination of ion-exchange chromatography, hydroxyapatite chromatography, and gel filtration.