DekaBDE - en rapport från ett regeringsuppdrag

Thyroid hormones are important for brain  Interfering with thyroid hormones may be one way PBDEs cause health problems . Are children at a higher risk to PBDEs? Children have been found to have  7 Apr 2017 “We don't fully understand the health consequences of exposures to Laboratory studies in animals, however, have shown that PBDEs can  According to the JECFA, for the more toxic PBDE congeners, adverse effects margin of exposure (MOE) was used to assess the health risk of dietary PBDE  30 Nov 2016 PBDEs, a class of flame retardants widely used since the 1970s, have Health effects in humans possibly associated with PBDE exposure  16 May 2008 Observed Effects of Exposure to PBDEs Related to Thyroid. Hormone Assessing the potential human health risks from PBDEs poses several. 25 Oct 2016 Polybrominated diphenyl ether (PBDE) flame retardants: environmental contamination, human body burden and potential adverse health effects. 6 Apr 2017 Human health risk assessment based on bioaccessible concentrations of DDTs and PBDEs in fish showed that the maximum allowable daily  2 Sep 2008 PBDEs cause adverse health effects in humans at environmentally relevant levels. Exposure to PBDEs.

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What are the potential human health effects of PBDE? Few human data are available on health effects of individual PBDEs. Of the three commercial mixtures, pentaBDE seems to show toxicological effects at the lowest concentration. 4 Animal data suggest effects on the endocrine system (thyroid), neurodevelopmental and neurobehavioural effects and reproductive effects. PBDEs are found in a variety of consumer products, from TVs and toasters to mattresses and drapes.

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The prominent concern is effects on the developing nervous system. This is based on multiple studies of laboratory animals. Limited epidemiologic data exist on child health effects.

Pbde health effects

Välens miljökemiska och biologiska status 2012

Pbde health effects

Human studies already document adverse effects on intelligence and psychomotor skills in children with disruptions in thyroid levels in the womb through the second year of life. 19-22 One study found that workers exposed to PBDEs experienced higher prevalence of hypothyroidism.

Pbde health effects

(2001, 2002) and Viberg et al. (2004), will confound treatment effects with litter effects (Holson and Pearce 1992).
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These studies document that PBDEs are toxic to the brain, reproductive system and liver and disrupt thyroid function. 18 Effects on thyroid function provide a plausible mechanism for PBDEs’ possible adverse effects on Prasada Rao S. Kodavanti, Bommanna G. Loganathan, in International Encyclopedia of Public Health (Second Edition), 2017 Environmental Contamination and Human Exposure. PBDE residues have been detected in indoor air, house dust, and foods, making PBDE exposure to humans possible via multiple sources.

Polybromerad difenyleter (PBDE) är ett vanligt flamskyddsmedel som används för att minska risken för brand i en mängd olika produkter, till exempel  Vidare överskrider halterna av flamskyddsmedel (PBDE) kraftigt gällande MKN i fisk vid alla sta- tioner där högsta halterna Exponering för höga halter kan leda till ökad risk för bröst- och biomarkers of animal health status.
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19-22 One study found that workers exposed to PBDEs experienced higher prevalence of hypothyroidism. 23 Concurrent exposure to both PBDEs and PCBs, as from consuming some fatty fish, may present an increased risk since some researchers have found additive or synergistic effects between the two chemicals. 24 PBDE effects on the developing brain are receiving considerable attention in the public-health community. The possible association between PBDE exposure and neurodevelopmental effects was originally considered for a topic at the committee’s workshop on February 3, 2016, which was designed to explore potential case studies and to help the committee select the topics for its systematic reviews. Se hela listan på Background Polybrominated diphenyl ethers (PBDEs) are used as flame retardants in many household items. Given concerns over their potential adverse health effects, we identified predictors and evaluated temporal changes of PBDE serum concentrations. Methods PBDE serum concentrations were measured in young children (2-8 years old; N = 67), parents of young children (<55 years old; N = 90), and PBDEs biomagnify (increase in concentration) in food webs, exposing high trophic level species to levels that may cause health effects.